A postdoctoral position is immediately available in the Division of Pediatric Hematology, Oncology and BMT, University of Wisconsin School of Medicine and Public Health/Carbone Cancer Center (Otto Lab, PI: Mario Otto, MD, PhD). Our laboratory focuses on the development of targeted therapies for pediatric cancer, including hematopoietic stem cell graft engineering to allow for early post-transplant immunotherapy strategies for leukemias and solid tumors.
We currently have an opportunity for a postdoctoral researcher in an ongoing project that aims at developing a humanized mouse model that would allow for improved T cell reconstitution, including the engraftment of the important subset of gamma delta T cells. Ultimately, such a humanized model could serve as an improved pre-clinical model to test various forms of adoptive immunotherapies and allow investigating the role of gamma delta T cells in post-transplant engraftment and immune reconstitution.
Other fields of research in our lab pertain to tumor-targeted, molecular radiotherapy and cancer immunotherapy. We are interested in evaluating synergy and potency of combination therapies and identify the molecular mechanisms underlying their effect, with the goal to rapidly translate these findings from bench to bedside.
Specific duties include designing and utilizing research methodologies aimed at achieving the goals of the project; assistance or lead in writing of grants and manuscripts; regular data report; presentation of data at meetings; assist in the mentoring of undergraduate and/or graduate students. Additional duties as requested by the principal investigator. Must be able to, willing and cleared to work with rodent models and radiotherapeutics in a BSL-2 work environment. We offer a collegial, nurturing postdoctoral training environment critical for a future independent position in science. We provide ample laboratory and office space in a well-equipped lab in the Wisconsin Institute for Medical Research (WIMR). The University of Wisconsin–Madison is ranked amongst the top 15 public universities in the U.S. (US World and News Report 2018) Madison is a wonderful medium-sized college town with exceptional quality of life and affordable costs of living. Lab info: www.pediatrics.wisc.edu/research/research-groups/otto.
Candidates please send cover letter and resume (including 3 references) to the Principal Investigator, Mario Otto, MD, PhD, at email@example.com
Location/Region: Madison, WI (53701)